An Update on Cartilage Repair
Can an 81 year old gym rat regrow knee cartilage? It seems so. In July 2020, I was ramping up my leg-press load to see if I could get back to 10 plates per side (1000 lb including the sled). When I got to 8 plates per side on my last set that day, my left knee really...
Year-end Review of the Scientific Progress in Fighting Aging
Here is a very exhaustive review of scientific progress aimed at arresting and reversing aging from our friend Reason at FightAging.org; not yet accomplished, but there are many promising pathways leading forward. A Look Back at 2020: Progress Towards the Treatment of...
Maintaining Muscle Mass into Advanced Age Reduces All-cause Mortality
The study that triggered this article is titled "Mechanisms by which Calorie Restriction Delays the Onset of Sarcopenia", which I think misses the point entirely. The article points out that CR is very effective at life extension in short-lived species, but not nearly...
Decades More Health-Span Possible with Frank’s Coaching at Fitness19, Simi Valley
Frank Wilhelmi: Senior Fitness Specialist & Trainer Exercise Training to build Muscle/Strength, Vaporize Fat, Boost Stamina - Move with Grace and Ease Diet/Nutrition - for Optimal Health, Fitness & Longevity Supplements - to Counter Functional Losses of Aging,...
Update on Plasma Dilution as a Regenerative Strategy to Mitigate/Reverse Aspects of Aging – A Pivotal Outcome
Diluting blood plasma in old mice (or people) by 50% restores youthful functions in a broad range of systems, in both body and brain!
Update on Potential Prostate Cancer Treatement
On September 18, 2019 I had an MRI that found two suspicious loci in my prostate, one of which was diagnosed as likely stage 1 Prostate cancer and the other as transitional, I chose to try an underground approach shown to be selective at killing cancer cells via 4...
Watch this 80 yr-old Best Leg Press
Watch This 80 YEAR-OLD Do His Lifetime-Best Leg Press How did I manage this? By using practical strategies to stay fit decades longer than most, and I want to show you how. Two weeks after my 80th birthday, I did my life-time heaviest leg press set: 900 lbs of plates...
Senolytic Therapy Improves Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy is well known for causing peripheral neuropathy - a tingling or burning in the hands and feet or perhaps simply numbness in extremities. Now there is evidence that this is caused by Cisplatin and other chemo-drugs inducing a state of senescent-like injury...
Study finds Hydroxychloroquine Reduces in-Hospital COVID-19 Mortality
August 25, 2020 Study finds hydroxychloroquine reduces in-hospital COVID-19 mortality by Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S. An Italian observational study contributes to the ongoing debate regarding the use of hydroxychloroquine in the current...
Adenosine Injections Regrow Knee Cartilage – (In Mice)
Adenosine Injected into Arthritic Joints Produces Cartilage Regrowth; so says the press release regarding a study cited at: https://doi.org/10.1038/s41598-020-68302-w. This is a promising outcome; between 50% and 35% regrowth in mice injected with a liposomal...
Could We Kill this Epidemic in a Month?
The world has been dealing with this Corona virus since late December 2020, and China before that. Data on the severity of outcomes has been gathered from around the world, showing that severity is highly dependent on Vitamin D status. We in the US typically use the...
Great Promise for Stem Cell Vesicles in Life Extension
Over a decade ago, stem cells were promised to repair virtually everything in our bodies, but over time researchers noticed that very few stem cells actually survive transplanting over the long term, and began looking at what stem cells (SCs) were doing to cause the...