Drugs or Supplements???

Drugs or Supplements???

I personally am losing patience with the pace of release of products to fight or reverse aging. This is like swimming in molasses - really slow moving and expending tremendous energy (resources like money and more importantly time). The drawback for the Drug pathway...

Here is a surprising (to me) outcome of a mouse gut biome study that increases longevity and lowers inflammation in aged mice. Surprising because the presence of gram-negative bacteria, which normally increase inflammation because they constantly shed their highly...

A Good Cover Article on Klotho and Aging

A Good Cover Article on Klotho and Aging

In Greek Mythology Clotho is the one of the Three Fates or Moirai who spins the thread of human life; in our biology Klotho is a trans-membrane receptor structure, parts of which also circulate in our blood, that influences lifespan in many ways. For those who want to...

New Hope for Reversing Cognitive Decline; Senolytics

New Hope for Reversing Cognitive Decline; Senolytics

A definitive mouse study shows that several forms of stress increase multiplication rates of brain immune cells, leading to early senescence in those cell populations, and that leads to damage of neurons and cognitive decline, potentially including Parkinson's,...

The Promise of iPSC Vesicles for Vertebral Disk Repair

The Promise of iPSC Vesicles for Vertebral Disk Repair

Take any old skin cell (or a million or so), add the four Yamanaka Factors reversing it's/their age to make it/them into near embryonic stem cells (induced pluripotent mesenchymal stem cells or iMSCs), feed them and let them multiply, then harvest the signaling...

The State of Senolytic Drug Development and Deployment

The State of Senolytic Drug Development and Deployment

Senolytic drugs (or compounds) are a promising tool for reducing the impact of aging, potentially pushing the onset of the diseases of aging out into the far future. So how far along are we to deploying this potential tool for the average citizen's benefit? There are...

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