Sendoff for 2022
On this last day of 2022, I am in day 5 of my first Covid-19 infection, having finished day 3 of Paxlovid anti-viral therapeutic drug, and feeling very much like I have it beat. Within a half hour of the first dose the disease trajectory had reversed from rapid...
Update on My Strategies for Longevity
Here are two notable sources of technical stuff on NOT AGING, followed by supplements I use to aid in that effort: https://www.fightaging.org/: Written by a bright guy with the name Reason; he puts up three articles per week-day without fail. Format is: Study Title,...
Apigenin – A Promising Compound found in Chamomile and Parsley can Greatly Improve Health
I started looking (yet again) for ways to improve my sleep; to fall asleep faster and make sleep more restorative. Chamomile is noted for relaxation so I was looking for a stronger extract of chamomile or at least the sleep-inducing part of it, thought to be a...
Frank’s New Training Gig at Island Health & Fitness
Hire me, Frank Wilhelmi, Senior Fitness Specialist, BS, ME, CFT, as your Personal Trainer and I will give you skills to keep an aging body in top shape into your 80s, 90s and beyond! Let me (at 83) show you strategies that work life-long to sustain real long-term...
Frank’s New Training Location
Fitness 19 Simi Valley is no more! With the closure of Fitness19 Simi Valley, I'm moving my operation to Island Health and Fitness at 5750 E Los Angeles Ave., 93063. It's a less frenetic club than F19, fewer occupants and easier access to equipment. I plan to keep the...
Reality Check on Stem Cell Exosomes for Regeneration
I have high hopes that Stem Cell exosomes will prove to be the Thor's Hammer for regeneration and a tool for greatly extended lifespan. Like most hopes, realty is generally more complex than hope envisioned. Stewing up vast batches of stem cell exosomes to be used by...
Kidney Function Improvement Related to Boosting Klotho Production
I have long-time friend who has experienced failing kidney function over the years. Recently he reported he was on a transplant list and his GFR had fallen to 6%. I had been researching Klotho, the natural protein expressed primarily in the kidneys, and has strong...
Drugs or Supplements???
I personally am losing patience with the pace of release of products to fight or reverse aging. This is like swimming in molasses - really slow moving and expending tremendous energy (resources like money and more importantly time). The drawback for the Drug pathway...
Here is a surprising (to me) outcome of a mouse gut biome study that increases longevity and lowers inflammation in aged mice. Surprising because the presence of gram-negative bacteria, which normally increase inflammation because they constantly shed their highly...
Merry Christmas & Happy New Year Wishes – (Hopefully better than this one!!)
I just got back from my one-hour shift at the gym training my one client of the day (we closed early for Christmas), but let me tell you, I find this phase of my life the best yet. Yes some parts of this old body are not as functional as in my youth, but I am so...
A Good Cover Article on Klotho and Aging
In Greek Mythology Clotho is the one of the Three Fates or Moirai who spins the thread of human life; in our biology Klotho is a trans-membrane receptor structure, parts of which also circulate in our blood, that influences lifespan in many ways. For those who want to...
Update: Old vs Young Blood and Extra-Cellular Vesicles Carry Some of The Longevity Magic
Last year we learned that simply diluting old blood in the aged lets them function like younger (animals and humans) (Reference). Still, the search is continuing for youth factors in young blood that might also allow reversing some of aging. A new study has shown that...