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( Anti-aging) Anti-aging medicine refers to attempts to extend maximum or average lifespan by slowing down or reversing the processes of aging. Some researchers in this area (known as biogerontology) and "life extensionists" or "longevists" (who wish to achieve longer lives for themselves) believe that future breakthroughs in tissue rejuvenation with stem cells, organ replacement (with artificial organs or xenotransplantations) and molecular repair will eliminate all aging and disease as well as allow for complete rejuvenation to a youthful condition.

The sale of putative anti-aging products such as nutrition, physical fitness, skin care, hormone replacements, vitamins, supplements and herbs has become a lucrative industry, with the US market generating about $50 billion of revenue each year. Medical experts state that the use of such products has not been shown to affect the aging process. Many claims of anti-aging medicine advocates have been roundly criticised by medical experts, including the American Medical Association. Bioethicists question whether and how the human lifespan should be extended.

Average lifespan in a population is lowered by infant and child mortality, which are frequently linked to infectious diseases or nutrition problems. Later in life, vulnerability to accidents and age-related afflictions such as cancer or cardiovascular disease play larger roles. Extension of average lifespan can be achieved by good diet, exercise and avoidance of hazards such as smoking. Maximum lifespan is determined by the rate of aging for a species inherent in its genes and probably by certain environmental factors. Currently, the only widely recognized method of extending maximum lifespan in organisms such as nematodes is calorie restriction. Theoretically, extension of maximum lifespan could be achieved by reducing the rate of aging damage, by periodic replacement of damaged tissues, or by molecular repair or rejuvenation of deteriorated cells and tissues.

Much of anti-aging medicine has been concerned with the use of nutrition, in the form of diets or supplements, to extend lifespan. The many diets promoted by anti-aging advocates are often contradictory. One of the few areas of consensus among nutritionists is the importance of keeping stable blood sugar levels, achieved in part by managing the glycemic indices of food choices.^{[citation needed]} Two diets with different approaches and some support from scientific research are the Paleolithic diet and Caloric restriction.^{[1][2][3][4][5]}

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