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( Tryptophan)
Tryptophan (abbreviated as Trp or W)[1] is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in genetic code as the codon UGG. Only the L-stereoisomer of tryptophan is used in structural or enzyme proteins, but the D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan).[2] The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. The isolation of tryptophan was first reported by Sir Frederick Hopkins in 1901 [3] through hydrolysis of casein. From 600 grams of crude casein one obtains 4-8 grams of tryptophan.[4] Plants and microorganisms commonly synthesize tryptophan from shikimic acid or anthranilate.[5] The latter condenses with phosphoribosylpyrophosphate (PRPP), generating pyrophosphate as a by-product. After ring opening of the ribose moiety and following reductive decarboxylation, indole-3-glycerinephosphate is produced, which in turn is transformed into indole. In the last step, tryptophan synthase catalyzes the formation of tryptophan from indole and the amino acid, serine. The industrial production of tryptophan is also biosynthetic and is based on the fermentation of serine and indole using either wild-type or genetically modified E. coli. The conversion is catalyzed by the enzyme tryptophan synthase.[6]
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Tryptophan Subcategories
Tryptophan Articles
Use Tryptophan To Boost Your Levels Of The Feel-Good Hormone by Steve Smith
stephensmith45@aol.com.
Best regards
Steve Smith
http://www.sisyphuspublicationsonline.com Use Tryptophan To Boost Your Levels Of The Feel-Good Hormone
Tryptophan is one of the ?essential? amino acids;
?essential? in this contex...
Are you a Turkey When it Comes to L-Tryptophan? by Lucho Crisalle Rd
Here in the U.S., Thanksgiving is the start of the holiday season and most people look forward to the Thanksgiving dinner all year long - turkey, mashed and/or sweet potatoes, gravy, cranberry sauce and of course, pie. Yummmm. You could easily cons...
Improve Your Mood with 5-HTP Supplements by Chester Ku-Lea
What is 5-HTP? The Griffonia Extract is rich in 5-HydroxyTryptophan (5-HTP), which comes from an African vegetable, the Griffonia simplicifolia seed, and contains 30% 5–HTP. 5-HTP is an amino acid that is a direct precursor of serotonin, an import...
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