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( Trypanosome) Blastocrithidia
Crithidia
Endotrypanum
Herpetomonas
Leishmania
Leptomonas
Phytomonas
Trypanosoma
Wallaceina

The most important trypanosomal diseases are trypanosomiasis (African Sleeping Sickness and South American Chagas Disease); these are caused by species of Trypanosoma. The Leishmaniases are a set of trypanosomal diseases caused by various species of Leishmania.

A variety of different forms appear in the life-cycles of trypanosomes, distinguished mainly by the position of the flagellum

Most trypanosomes have at least amastigote and promastigote stages. Trypanosoma appears in all five forms, with the trypanosomal stage occurring in the vertebrate host. Trypanosoma brucei sub-species have two forms in the bloodstream of a vertebrate host, the rapidly dividing long-slender form and the non-dividing short stumpy form. The short stumpy parasites are adapted for uptake into the tsetse fly vector, and are non-proliferative in comparison with the slender forms.

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