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( Sphingomyelin) Sphingomyelin(SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents ~85% of all sphingolipids.

In humans, it is the only membrane phospholipid not derived from glycerol.

Like all sphingolipids, SPH has a ceramide core (sphingosine bonded to a fatty acid via an amide linkage). In addition it contains one polar head group, which is either phosphocholine or phosphoethanolamine.

The function of sphingomyelin remained unclear until recently when it was found to have a function in signal transduction.

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