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( Protein synthesis) A protein is a naturally occurring aliphatic compound, composed of amino acids (aa) and containing primarily at least the elements carbon (C), hydrogen (H), nitrogen (N), and oxygen (O). Many proteins also contain sulfur (S), occasionally phosphorus (P), and sometimes iron (Fe).

In biosynthesis, precursors are activated often by nucleotides, generally in the presence of a catalyst, oxidizing or reducing agent, to interconvert[1] biochemicals within living organisms.

For synthesis of protein, a succession of tRNA molecules charged with their appropriate amino acids have to be brought together with an mRNA molecule and matched up by base-pairing through their anticodons with each of its successive codons. The amino acids then have to be linked together to extend the growing protein chain, and the tRNAs, relieved of their burdens, have to be released. This whole complex of processes is carried out by a giant multimolecular machine, the ribosome, formed of two main chains of RNA, called ribosomal RNA (rRNA), and more than 50 different proteins. This evolutionarily ancient molecular juggernaut latches onto the end of an mRNA molecule and then trundles along it, capturing loaded tRNA molecules and stitching together the amino acids they carry to form a new protein chain.[3]

1. Initiation - A ribosome attaches to the mRNA and starts to code at the FMet codon (usually AUG, sometimes GUG or UUG).

Protein synthesis Subcategories

Protein synthesis Articles

How to Achieve a Positive Nitrogen Balance by Mike Westerdal
If you've never heard of a "positive nitrogen balance" and are wondering what the hell I'm talking about don't feel bad, you're not alone. The term isn't something you hear every other guy in the gym talking about. But I can guarantee that even thoug...

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