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( Prodrome)
In medicine, a prodrome is an early non-specific symptom (or set of symptoms) indicating the start of a disease before specific symptoms occur. For example fever, malaise, headache and anorexia (lack of desire to eat) are part of the prodrome for mumps or a variety of infective disorders. A prodrome can be the precursor to the onset of a chronic neurological disorder such as migraine or epilepsy, where prodrome symptoms include scotoma, disorientation, aphasia, or photosensitivity. It also refers to the initial in vivo round of viral replication. A prodrome for schizophrenia has become more frequently appreciated since 1996. [1] The term "ultra-high risk mental state" is sometimes preferred, as a prodromal period can not be confirmed until the emergence of the illness has occurred. [PMID 16677803]
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