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( Passenger virus) A passenger virus is a virus that is frequently found in samples from diseased tissue, such as tumours, but does not contribute to causing the disease.

Proving that a virus has no causative role can be difficult. Although none of the following signs is definitive, evidence that a virus found in diseased tissue is a passenger rather than a causative agent includes

A well-established example is lactate dehydrogenase virus, which is often found in mouse tumours.[1] Hepatitis G virus and Chandipura virus are possible examples in humans.[2][3] The Duesberg hypothesis posits that HIV is a passenger virus in the etiology of AIDS.[4]

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