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( Kinase)
In chemistry and biochemistry, a kinase, alternatively known as a phosphotransferase, is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation (An enzyme that removes phosphate groups from targets is known as a phosphatase.) One of the largest group of kinases are protein kinases, which act on and modify the activity of specific proteins. These are used extensively to transmit signals and control complex processes in cells. Up to 518 different kinases have been identified in humans. Their enormous diversity and role in signaling makes them attractive targets for drug design. Various other kinases act on small molecules (lipids, carbohydrates, amino acids, nucleotides, and more), either for signaling or to prime them for biochemical reactions in metabolism. These are named after their substrates. name="See_also" id="See_also">
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Kinase Subcategories
Kinase Articles
"Japanese Wonder" Supports Healthy Circulation, Blood Pressure and More! by Dr. Williams' Mountain Home Nutritionals Team
Dear Reader, As you've discovered by now, Dr. Williams spends a great deal of time researching and traveling the globe. One of the countries he's focused on most intently over the past year or two is Japan. Japan has one of the...
Vitamin D antimetastasis mechanism reported by Life Extension
Life Extension Update Exclusive
Vitamin D antimetastasis mechanism reported
The January 2006 issue of the journal Carcinogenesis reported the findings of researchers at the University of Rochester Medical Center that vitamin ...
Elevated creatine kinase activity in primary hepatocellular carcinoma
Elevated creatine kinase activity in primary hepatocellular carcinoma
Georg Meffert , Frank N Gellerich , Raimund Margreiter and Markus Wyss
Department of General and Transplant Surgery, University Hospital, Anichstrasse 35, A...
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