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Article Topic: sarcopenia
Sarcopenia (from the Greek meaning "poverty of flesh") is the degenerative loss of skeletal muscle mass and strength associated with aging. Sarcopenia is a component of the Frailty syndrome. 0.5-1% of loss per year after the age of 25 At present, there is no generally accepted definition of sarcopenia in the medical literature.[1] The European Working Group on Sarcopenia in Older People (EWGSOP) has developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia.[2] For the diagnosis of sarcopenia, the working group has proposed using the presence of both low muscle mass + low muscle function (strength or performance). Sarcopenia is characterized first by a decrease in the size of the muscle, which causes weakness and frailty. However, this loss of muscle mass may be caused by different cellular mechanisms than those that cause muscle atrophy. For example, during sarcopenia, there is a replacement of muscle fibres with fat and an increase in fibrosis.
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