Strategies for Slowing the Processes Involved in Aging, and Delaying their Consequences

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Anti-aging - Slowing the processes involved in aging, and delaying their consequences. We all age, we will all die; those are the unavoidable facts. The only thing we have some control over is whether, by our lifestyle and actions, we slow the process or speed it up. Over the social history of civilization, our great writings and traditions have upheld norms of behavior and action that seem to lead to fuller and longer life, warning us against those things that make life less worth living and shorten it. We all understand that there are activities that can lead to sudden death or maiming, where great (maybe manageable) risk is traded for intensity of feeling. And, on the other hand there are behaviors that lead to isolation, boredom, and a living death. In between, there are things we can do to maintain our physical and mental capacity to live life to the fullest - and the longest. We propose Six Critical Keys to Dynamic Senior Living that are set up as topical categories in the central section of our home page. These categories deal with endeavors, behaviors and actions that we know to enhance our capacity to live life to the fullest. These are: ANTI-AGING, EXERCISE, NUTRITION, REST/RECOVERY and RELAXATION, SUPPLEMENTS and THINKING/ATTITUDE. Our goal is to keep you up to date on the latest (and the time-tested) information available in these categories. In this ANTI-AGING category our goal is to detail the actual mechanisms of aging and what science is uncovering that will aid us in slowing its progress. Four major aging mechanisms have come to light in recent years. These are: OXIDATIVE DAMAGE - damage by ‘free radicals’ at the molecular level, GLYCATION/GLYCOSYLATION - bonding of sugars to proteins that stiffens tissues and destroys their function, INFLAMMATION - a repair process that becomes more prominent, damaging and indiscriminant as we age, SENESCENCE - cells stop dividing after about 50 divisions due to loss of our chromosome’s telomere length; seems to set maximum lifespan limit. Slowing the aging process is accomplished by doing things that inhibit the damage from these aging mechanisms or slow the rate at which the damage is done. In some cases there is hope that specific types of damage can actually be reversed, and we could, in fact, grow younger in some respects. Oxidative damage: Oxidation is the primary means of energy generation in most living organisms. It occurs through sequential chains of enzymatic chemical reactions within cells. At intermediate stages in these reactions, electrically charged ions are produced that, if left to wander, can interact with nearby molecules, causing damage to their chemical structure. The body manufactures antioxidants to manage these energetic ions. For the most part, antioxidants function in a sequence of cascaded reactions involving several antioxidants, wherein the energy of a free radical is disbursed harmlessly. There are two general categories of antioxidants - antioxidants you make internally (endogenous) and those you obtain from diet. Endogenous antioxidant molecules are usually built around certain minerals, and unless you obtain the required minerals through a diet rich in mineral sources, your antioxidant production will be hampered. Selenium is one such mineral. The reason vitamin C is so effective at resolving many ills is that we can’t make it. A large dog makes about 10 grams a day, but we and the apes have lost the ability to build it; we have to get it in our diets. It is involved in numerous pathways of free-radical reduction, so for anti-aging purposes we need a plentiful and continuous supply. But taking vitamin C, while necessary, is not sufficient, not the best we can do. We need a bouquet of antioxidants in our diets, and recent discoveries have shown the fruits and vegetables are the primary source for those. The plant world has developed an array of them for protection against sunlight and other elements of the environment, and nature has cleverly set our bodies up to use them to the fullest when we eat them on a regular basis. The value of taking antioxidants, and eating the foods that are rich in them, is that they partially make up for the decline with age of our own antioxidant production. One of our primary antioxidants is superoxide-dismutase. The –ase on the end signifies an enzyme, and this antioxidant enzyme disarms the superoxide radical, a product of metabolism in every cell that is extremely damaging unless arrested shortly after formation. Superoxide-dismutase is one of those enzymes that if taken by mouth, doesn’t make it to the cellular level – it gets destroyed in the digestive system. And its production decreases with age, leaving you more susceptible to free-radical damage. The only approach is to convince our bodies to make more of it. The technology now exists to do just that. Read more. Research suggests that consumption of antioxidant-rich foods reduces damage to cells and biochemicals from free radicals. This may slow down, prevent, or even reverse certain diseases that result from cellular damage, and perhaps even slow down the natural aging process. This is the basis for the free-radical theory of aging. Step one, then, to retard aging is to start eating anitoxident-rich foods and using supplements that foster antioxident production to counter the natural decline that occurs with age. It would be helpfull to have started this when you were a child, but today is the best day to start otherwise. My favorite product, and the most complete anti-aging formula I have found, is Life Extension Foundation's Life Extension Mix. Nothing comes even close to its comprehensiveness. It's not cheap, but I personally think my health is worth it. Strategy: Eat a wide variety of fresh fruits and vegetables, preferably organic; take a broad-spectrum antioxidant supplement; take supplements that increase endogenous antioxidant production. Glycation/Glycosylation - blood sugar damage: People with diabetes wear out early - type I, type II, or metabolic syndrom - high blood sugar wreaks havok with all the body's tissues. The blindness, heart disease, neuropathy, circulation loss in the feet - all those amputations and nightmare complications are caused by proteins getting denatured by bonding with sugar molecules. Actually, the process of sugar molecules bumping into proteins and bonding to them happens in normal metabolism, with normal blood sugar levels; it just happens a lot faster when blood sugar is elevated. The harm occurs because whatever function a protein was performing before bonding to a sugar, it can no longer perform that function. These protein-sugar molecules are referred to as 'Advanced Glycation End-Products or AGEs. AGEs, once formed, are essentially permanent, and stick where they were formed. The cell wall, or whatever part of whatever organ was altered, stays incapacitated for life.There are mechanisms for removing AGEs that the body uses to heal the damage; they just don't work as well as we would need to get us into our 100s with youthfull vigor under normal living conditions. Two words are used for this process, because glycation is a non-enzymatic reaction (the sugar latches onto a protein on its own power) while glycosylation is enzyme-assisted. Glycosylation is a deliberate process used by the body to form glycoproteins for a multitude of reasons, but sometimes creates a residue that must be eliminated; glycation is a reaction that is always an accident, and a liability of using sugar for fuel. Very simply, you minimize glycation damage by keeping blood sugar levels low. You can count on the fact that every sugary soda you ever drank has left a mark on you. Every time you pushed your blood sugar above 100 mg/dl, a little bit of extra aging took place. We can keep blood sugar under control by eating frequent, small meals, by avoiding confections, candy and pastries, by lowering our intake of starchy foods, by eating fiberous vegetables with most meals and by eating whole fruit rather than drinking juices. Watch out for juices labled 'drink' or 'cocktail' because they contain various forms of sugar rather than just juices. The trick is to get the digestive system to release sugar into the blood stream at a slow rate. Both fiber and fat slow the release of sugar into the blood; that's why low-fat anything is a usually worse in this regard than the real thing. Low-fat ice cream will spike your blood sugar rapidly, while real 'iced cream' will hardly cause a blip even though it has lots of sugar. Make desserts rare treats, and eat them only when your stomach is already working on real foods. Eat small, never eat until uncomfortably full and eat real, whole foods. Many supplements are available to down-regulate chronic high blood sugar. The mineral chromium, alpha-lipoic acid, cinnimon extract, corosolic acid, grape-seed extract, the herbs Gymnema Sylvestre, Vaccinium myrtillus (Bilberry) and Galega officinalis, which is protective of the pancrease. However, the real trick is diet, and the elimination of those foods that raise blood sugar appreciably. The unseen side of this controversy is insulin level. If you are insulin-resistant, you can have normal blood sugar levels AND have chronically high insulin levels. It has now been shown that insulin itself is inflammation-promoting and contributes to the rapid aging of many tissues. The combination of high blood sugar and high insulin is the fast track to rapid aging. The only proven strategy to life sxtension to date is caloric restriction; many researchers now believe that much of that result is simply due to blood sugar restriction accompanied by sustained low insulin levels. A really good reference can be found at found at Dr. Mercola's site. Strategy: Eat small and frequent meals; get off grain-based and starchy foods which raise blood sugar and insulin; eliminate sugar-based drinks and sodas; forget desserts and sweets most of the time. Read our Nutrition Category for much more information. Inflammation: Inflammation in all the body's tissues increases, in general, as we age. Why this is true is not well understood, but inflammation seems to be a common property and possible underlying cause of many of the chronic diseases that afflict the aging. Inflammation is also one of the mechanisms used by the immune system to fight invaders and heal injury, so it is almost as though the aging body increasingly sees its own tissues as an enemy or that there is a chronic state of injury that needs constant attention to promote healing. But inflammatory processes eventually become the source of much of the damage evident in the aging body. Inflammation is the key initiating factor in major degenerative diseases. In fact, some scientists estimate that inflammation underlies up to 98% of the diseases afflicting humans, including a vast array of seemingly different conditions such as cancer, heart disease, diabetes, and neurodegenerative disorders. We talked above about elevated insulin as inflammatory, but there are several other known factors that promote inflammation. One prominent factor is nuclear factor-kappa beta or NFkB. NFkB is a protein that acts as a switch to turn inflammation on and off in the body. Scientists describe NFkB as a "smoke sensor" that detects dangerous threats like free radicals and infectious agents. In response to these threats, NFkB "turns on" the genes that produce inflammation. As we age, NFkB expression in the body increases, provoking widespread chronic inflammation and setting the stage for diseases ranging from atherosclerosis and diabetes to Alzheimer’s. Knowing this simple fact should motivate us to find ways to counteract NFkB’s deleterious effects and thus delay or avoid many of the diseases commonly associated with aging. Follow this link to a very informative article on this site that details the effective dietary ways to lower NFkB's level and impact - a 'must read' if you want to understand how to deal with inflammation. Virtually all the measures cited in this article to lower NFkB reduce the other important causes of inflammation. People suffering from chronic disease often have elevated levels of C- reactive protein in their blood. C-reactive protein indicates an inflammatory process is going on in the body, but does not identify the specific pro-inflammatory cytokine that may be the underlying cause. Some of the important inflammatory cytokines are: Tumor necrosis factor alpha (TNF-a), Interleukin-1 beta (IL-1b), Interleukin-6 (IL-6) and Interleukin-8 (IL-8). Testing for pro-inflammatory cytokines has been prohibitively expensive because there has been so little demand for it. Recently, the Life Extension Foundation spent more than a year establishing a relationship with the largest blood-testing laboratory in the United States to offer an inflammatory cytokine profile at an affordable price. (Currently $435.00 for Members) If you are elderly, or suffer from any serious disorder, these cytokine tests can enable your doctor to prescribe therapies that specifically target the inflammatory cytokine responsible for your poor state of health. Strategy: Foremost - block production/expression of NFkB; eat foods that do that, find and take supplements that suppress it; read the article linked above and act on its information. A work in process; more to come. Related Articles: Aging   Oxidation   Glycation   Inflammation   Senescence   antioxidants   superoxide-dismutase

1. Anti-Aging Facts & Myths by William M. Garnier Every single one of us begins aging the moment we are born - If you’re alive, you’re aging - you can’t avoid it. But there are a number of things that you can do to keep yourself healthy and active, and to eliminate or at least slow down many of the factors that contribute to aging. Ever since Ponce de Leon went searching for the Fountain of Youth, people have been lookin ...more...

2. How to Prevent Oxidative Stress by Matthew Keegan Oxygen is necessary for humans. To breathe as well as product energy, our bodies require the use of oxygen. Organisms known as free radicals are produced as our bodies use oxygen. Oxidative stress is caused when these free radicals interact with the various cells in our bodies and essentially damage those cells. As a result the cell’s membrane, proteins and even genes are affected. Many disea ...more...

3. Goji Berries: The Anti-Aging Wonder Food by Sylvia Riley Copyright 2006 Sylvia Riley Goji berries are one of the most nutritionally dense foods on earth and house a staggering concentration of vitamins, minerals, amino acids, phytochemicals and essential fatty acids. Originating in Tibet and greatly favoured in traditional medicine, these scarlet berries have a mild sweet flavour mid that of a cherry and a cranberry. Aside their many noted health ...more...

4. Moderate exercise may attenuate some aspects of immunosenescence by Moderate exercise may attenuate some aspects of immunosenescence Nadzieja Drela1 , Ewa Kozdron2 and Piotr Szczypiorski3 1Department of Immunology, Warsaw University, Warsaw, Poland 2Department of Recreation, Academy of Physical Education, Warsaw, Poland 3Department of Sports Medicine, Academy of Physica ...more...

5. Cranberries, A Wonder Food That Tastes Great And Full Of Goodnes... by roger wakefield What is the 'cranberry berry', and why is it as good as everyone says? The Cranberry bush is a somewhat innocuous evergreen dwarf shrub usually discovered in sharp marshlands in the chillier areas of North America. The cranberry 'berry' initially appears as a simple white colour, but as it grows and becomes ripe it changes gradually to a rich burgundy colour. Altho ...more...

6. What Have We Learned From Antiaging Research? by Clive Jenkins An immense aspect of avoiding premature aging would be the fact that we have positively found out which methods were good or bad for us, and still if we did not yet find the foundation to bring to a halt aging overall, we have learned a lot about antiaging research. Allow me to show you what we have been taught up till now about antiaging research. Two Rules to Follow Diet and ...more...

7. Longevity Genes and Caloric restriction by Xi Zhao-Wilson, PhD, and Paul C. Watkins, SM, LE Magazine July 2006 Scientists Say Rapidly Advancing Technologies Hold the Key to Extending the Human Life Span Groundbreaking research funded by the Life Extension Foundation and conducted at BioMarker Pharmaceuticals in northern California is unraveling the factors responsible for aging and disease, as well as strategies and technologies that may one day help us live in goo ...more...

8. Why Do We Age? | 7 Theories of Aging by Dr. Richard Feely Why do we age? Currently, there are seven theories on the aging process. Actually, we do not have a good scientific explanation for aging. We just know that our bodies were designed to grow old. There are seven major theories about why we age. All of them have some credibility. The first is that our genes program ourselves to divide a certain number of times and once this divisio ...more...

9. Small Molecule Increases Lifespan and by John Lacey, Harvard Medical School Risk of Death Cut By 31 Percent for Obese Mice Treated with Compound, and Treated Mice Seen Living as Long as Lean Mice In Obese Mice, Molecule Reversed Nearly All Pathways Activated In Mice By High Calorie Diets Findings Suggest Broad Implications for the Treatment of Age-related Diseases, Including Diabetes and Heart Disease BOSTON-November 1, 2006-Researcher ...more...

10. The Usefullness of Collagen Cream by Anne Harvester There are many reasons why Collagen cream and other collagen products can be quite useful. The primary reason is that it helps in maintaining a younger-looking appearance as we get older; by age 40, most of us have lost 30% of our natural collagen. Collagen products can help us t ...more...

11. Make your cells young again to combat atherosclerosis, improve c... by Contributing Editor: Health Sciences Institute, 6/1/2003 Members Alert Make your cells young again to combat atherosclerosis, improve circulation, and even reverse aging Angioplasty and coronary bypass are two of the most common surgeries performed today. But despite the procedures' widespread use, how successful are they really? Research tells us that up to half of all angioplasty patients experience restenosis (another blocka ...more...

12. Four For Life--Habits That Help You Live A Longer Life by Jason Witt When you receive the Seal you will begin to understand the value of life. A new study confirms just how you can lengthen your own life--quit smoking, eat more fruits and vegetables, exercise, and drink moderately. For 4 years in the mid-1990s, researchers polled 20,000 people in the UK. They asked them about their lifestyles and also took blood samples to find out how much fruits and v ...more...

13. Botox, Collagen and More: A Guide to Injectables by A Aaronson There are many different facial fillers being used by plastic surgeons today with a variety of uses and applications. Navigating through the options can be tricky. This guide outlines the major injectables and fillers available and what they do for specific wrinkles, fine lines, and facial sculpting. Collagen: Collagen is one of the most recognizable names when it comes to fillers. It is ...more...

14. Anti aging products and what aging signs to look for by Jason Bibb Copyright 2006 Jason Bibb Anti aging products It is well known that women are very concerned with their look, doing their best while trying to stay fit and young. The time stamps begin to be visible with women over forty, so they will be more interested in finding the best anti aging products. Before choosing those products, it is recommended that you should ask the dermatologist for a ...more...

15. Resveratrol: Cutting-Edge Technology Available Today by Terri Mitchell - Life Extension Magazine Wine. No other beverage has attracted the attention of modern medicine like this drink. Although it is most widely known for its benefits for the heart, wine has benefits against cancer, dementia, and other age-related diseases. Researchers in Denmark recently looked at 25,000 people to find out what drinking alcohol does to mortality and discovered that wine drinkers slash their ove ...more...

16. Uncontrolled High Blood Pressure: A Little-Known Failure of Conv... by Heather S. Oliff, PhD; LE Magazine August 2006 Sadly, millions of Americans who think their blood pressure is under control are wrong! Shocking evidence reveals that most people treated with antihypertensive drugs still have higher-than-optimal blood pressure.1,2 As a result, they remain at a heightened risk of suffering stroke, heart attack, and kidney failure. Because hypertension (high blood pressure) is a multifactori ...more...

17. Protect and Improve Your Health With Antioxidants by Hamoon Arbabi Every minute of every day the cells of our bodies are assaulted by particles called oxygen free radicals, also called oxidants. We cant escape free radicals because our cells produce the ...more...

18. Barley Grass by Brian Balster Barley Grass (hordeum) has become the new 'it' product for those in the know. It provides fast, easy alkaline minerals and has a host of health benefits. Barley grass is high in calcium, contains all 20 amino acids, and is great at helping the body heal itself. This super food is becoming the most popular drink among celebrities as they've seen its abilit ...more...

19. Inflammation: The New Medical "Bad Guy" by Bruce Bailey According to the latest medical theory, chronic inflammation is the root cause of almost every disease suffered by human beings. That’s right. Many doctors believe persistent, low-level inflammation paves the way for chronic disease, including those we usually experience late in life, e.g. arthritis, heart and kidney disease, and cancer. As a part of our immune response system, inf ...more...

20. The REAL Effects of Alcohol On Your Body - Part 1 of 2 by Marc David marc_david@hotmail.com. Best regards Marc David http://www.justaskmarc.com The REAL Effects of Alcohol On Your Body - Part 1 of 2 If you are curious as to the effects of alcohol on the body, this could be the most eye-opening article you will ever read. Many of us associate the effects of alcohol on the body with the heart, lungs, liver, brain, memory, etc. Furthe ...more...

21. Anti Aging and Antioxidants by claudia Budu Ph.D. Today, more than before people enjoy the luxury of travel and leisure time for outdoor sports which increases the exposure to solar radiation and pollutants. Due to harsh environment contact, our skin can suffer from damages such as: erythema, sunburns, early aging, even skin cancer. It has been shown that early aging and wrinkles are accelerated by solar light exposure of the skin. As a co ...more...

22. Anti-aging Supplements by Anand Dongre The desire for beauty and youth never ends. The urge to look young goes on increasing as the age starts overpowering you. As the age starts knocking at your door the feeling to look younger grows manifold. In today’s society the aging is seen as a threat and end to the charm of life. Then people leave no stone unturned to look younger. They try every method that boasts of giving them the youthful ...more...

23. Bursitis Tendonitis; Causes, Treatments and Remedies by Steve Madigan First things first. What exactly are tendons? Tendons are the elastic ligaments that will connect the muscle to the bone. If something happens with the tendons (such as a breakdown), tendonitis can and most probably occur. If tendonitis does occur, the person will experience inflammation and pain and you can possibly have a limited movement of the joint. Within the body there are sacs of ...more...

24. Can't or Won't by Glenn Antoine If there is one thing that I have learned in life is that people in general do not like change. There are any number of motivators that we could list here that would cause someone to make a change in their life. However, there is and never will be a motivator as powerful or more assured of getting change out of people as “pain”. As an example, I am sure that you know someone that simply ...more...

25. An introduction to Adult Stem Cells by Matt Canham I'm sure you've already heard about Stem Cells. Maybe you saw a news story or a read a news article or saw the Presidential address. They are the most widely publicized scientific discovery today and with good reason. How about Embryonic Stem Cells? They have created a great deal of controversy and with good reason. The lure of what Embryonic Stem Cells can do for our health has led to e ...more...

26. Alternatives to Cosmetic Surgery by Joshua Berkowitz While it is true that beauty is only skin deep and it is the person “inside” who is most important, we are all being judged constantly on how we look and dress. Most people, especially in competitive work and social environments want to look as youthful as possible for as long as possible to enhance their prospects of success. There is a rapidly growing trend in most western countries to accept co ...more...

27. Anti-aging Supplements for Youth by Anand Dongre The quest of eternal youth is never ending and as we age, there is a thirst to look younger. This is a general scenario of the present society, where ageing is seen as a threat and we all tend to join the bandwagon. This brings us to have awareness of products that are meant to slow down ageing. Not all, but a few of these products and supplements are really effective against ageing and can slow ...more...

28. Free Radicals - Should I Be Concerned About Them? by Paul Wallace Free radicals are unstable molecules with extra "free" electrons looking for a connection. They can latch onto a cell membrane or blood vessel lining and create constant inflammation, leading to eventual damage, serious disease, and even to an early death. Free radicals are atoms or groups of atoms that contain at least one unpaired electron that attack healthy cells. If an electron is unpaired ...more...

29. Glutathione - Your Brain's Master Antioxidant Defense by Priya Shah Copyright 2004 Priya Shah Free radicals and oxyradicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, schizophrenia and Down syndrome. Glutathione is the brain's master antioxidant and plays an important protective role in the brain. According to Dr. Jimmy Gutman, "The brain ...more...

30. Curcumin: An Anti-Aging Herbal by Dr. David Orman Turmeric (Curcuma longa) is a plant native to south India and Indonesia. Its tuberous rhizomes have been used from antiquity as a condiment, as a textile dye, and medically as an aromatic stimulant. Curcumin is the substance that gives the spice turmeric its yellow color. Curry powder which is extensively used in Indian cuisine, is largely made of turmeric. Curcumin contains many po ...more...

31. These Thugs are Attacking You! by Christine Illich A free-radical is a molecule or atom that is missing an electron. Free-radicals attack healthy cells within your body trying to steal an electron from them. Free-radicals are nothing more than thugs. All cancer is caused by free-radicals and the damage they do to your DNA. Your DNA holds the blue print for every cell that is created. All cancer is caused by mutated DNA. This is how DNA mutati ...more...

32. Alagebrium Demonstrates Important Cardiac Benefits in Diastolic ... by Alteon Inc./Vinay Thohan, M.D., Alagebrium Demonstrates Important Cardiac Benefits in Diastolic Dysfunction and Endothelial Function Studies - PEDESTAL and Endothelial Function Data Presented at the American Heart Association Scientific Sessions 2005 - PARSIPPANY, N.J., Nov. 15 /PRNewswire-FirstCall/ -- Alteon Inc. (Amex: ALT) announced today that data demonstrating the ability of its lead A.G.E. Crossli ...more...

33. Survive The Next 20 years by j shipper Life Extension When we talk about life extension we don't talk about keeping people alive through artificial means, we actually mean extending the normal, natural life of Man. Definition: Life is a multi-faceted concept. Life may refer to the ongoing process of which living things are a part; the period between the birth (or a point at which the entity can be considered to be li ...more...

34. Supplements to Counter the Aging Process – Part 3: Inflammation by Frank Wilhelmi This month we highlight Inflammation and supplements that control or reduce it. Inflammation, oxidative damage and glycation damage are all related and intertwined in the impact they have on the aging process. Reducing one will generally improve the others, because whenever tissues of any kind are damaged in any way, the repair mechanism begins with local inflammation. If you ...more...

35. Goji berries plant by Kirk Bachelder The goji berries come from a vine-like plant that can sometimes reach 15 to 20 feet in height. This is usually found in the Ningxia Province in China. Several people describe the goji berry plant as a mix between a grape vine, and a tomato creeper. Goji berry refers to the Chinese name for the bright orange–red fruit of the thorny and woody plant (shrub) Lycium babarum. There are ...more...

36. Curcumin: An Anti-Aging Herbal by Dr. David Orman Turmeric (Curcuma longa) is a plant native to south India and Indonesia. Its tuberous rhizomes have been used from antiquity as a condiment, as a textile dye, and medically as an aromatic stimulant. Curcumin is the substance that gives the spice turmeric its yellow color. Curry powder which is extensively used in Indian cuisine, is largely made of turmeric. Curcumin contains many po ...more...

37. Anti-Aging Programs - Eight Primary Aspects to Consider by Danny Nicholas I believe anti-aging is multidisciplinary and is based on individual choices. Anti-aging is a lifestyle! Each person chooses how to progress down a certain path to health and well being. Below is a list of factors to consider in designing your own personal anti-aging program. Rev Up Your Metabolism Aging is accompanied by a decrease in your metabolic rate and an associated increa ...more...

38. Antiaging skin care by Alicia Caldelas ‘Antiaging skin care’ is a very poplar concept in today’s world. Today everyone wants to hide their age using antiaging skin care procedures (and a number of people are successful too). However antiaging skin care is not achieved by any magic potion. ‘Antiaging skin care’ is about discipline. It is about being proactive. Antiaging skin care is retarding the ageing process. Here are a few tips fo ...more...

39. Fitness for Health and Wellbeing by Ann Stewart When you think of fitness, you may be thinking of well-toned bodies, rock-hard abs and generally, just a fit and outstanding physique. What if I told you that in order to be truly fit and feel great you don’t need to be a body builder? Fitness is more than exercise. If you think exercise and weight control are all there is to fitness, you may be surprised! Fitness is a lifelong ...more...

40. Fight the Aging Process with Natural Supplements by Fabiola Groshan The aging process brings about all sorts of manifestations and conditions, some of which can be really unpleasant for many people. Be it fat increase, hair loss, sexual problems, bone and muscle problems, insomnia, or decreased stamina and strength, these problems will occur with each individual at different stages in their lives. They are the result of decreased functionality of the organs in our ...more...

41. Say 'No' To Aging - How To Stay Young Forever by Michael Douglas We all have seen our grandparents and parents grow old and most of us protest against the idea of aging in the same ways they did. In fact, we look for safer, more convenient and medically sound way to live longer, empower ourselves, and remain healthy throughout life. We may refer to it as 'quality longevity.' The everyday choices that we make have a greater impact on us than genetics, which acco ...more...

42. Delaying Age-related Functional Decline - A Multi-Pronged Approa... by Frank Wilhelmi I don’t think I was the first to use the expression ‘age-related functional decline’, but I think it an excellent descriptive summary of what happens as we age. Aging, as we experience it, is the result of many related physiological processes slowing gradually, or in some cases rapidly. Everything that used to run at full tilt gradually slows to a crawl, and finally, one or more of these proces ...more...

43. Is There Antiaging Nutritional Supplement Hype? by Tomas Labas The Antiaging Nutritional Supplement Hype When it comes to nutrition, there is no better reason to use a supplement than just that; nutrition. Nowadays, there is even more reason to use supplements as an antiaging nutritional supplement not only takes care of supplementing your nutrition, but it also aids in antiaging benefits. You can’t expect to look ten years younger with these suppleme ...more...

44. The Remarkable Health Benefits of Pomegranates. by Ruth Polak Recent research has discovered some remarkable things about the humble pomegranate. It is said that they can help reduce your risk of heart disease, strokes, certain cancers and even impotence. This marvellous fruit should be included in everyone's diet as it is yet further proof of why the Medit ...more...

45. Intergenerational Activities for the Sandwhich Generation by Dorothy Breininger, Debby Bitticks and Lynn Benson Intergenerational activities - what exactly are they and how can great-grandparents, grandparents, parents, and children benefit from doing them? Combining childcare and eldercare is not a new concept, and with the high cost of day care for both children and elders, creating an intergenerational home seems to make sound financial sense for more and more families. Although poolin ...more...

46. Senior Fitness Strategies - Preventing heart Disease While Build... by Frank Wilhelmi Stiff Arteries and Soft Bones - An Aging Dilemma Explained by Lack of Vitamin K2 There is an epidemic of Heart Disease (or Atherosclerosis) on one hand and Osteoporosis on the other throughout most of the western world. We supplement gobs of Calcium, only to have it taken up by plaque in our arteries and other soft tissues, while our bones drop in density as we age. One ca ...more...

47. Curcuminoids – a new tool for managing arthritic pain by Paul Clayton We are all familiar with the spice turmeric - the yellow coloured spice in curry - but it does a lot more than taste good. In fact, it is being intensively studied for its role as a powerful pain reliever - and even an anti-ageing nutrient. The yellow colour of turmeric is due to pigments called curcuminoids. Turmeric belongs to the Zingiberaceae or the ginger family. Curcuminoids have a l ...more...

48. The Power of the Pomegranate by Michael Brooks Copyright 2005 Michael Brooks The juice from a pomegranate offers some of the worlds most powerful antioxidants. In fact, studies show that pomegranate juice has more antioxidants than other known antioxidant drinks such as red wine, green tea, blueberry juice, cranberry juice and orange juice. In addition, there are some studies that suggest pomegranate juice my help in the ...more...

49. Superoxide Dismutase, Boosting the Body’s Primary Antioxidant De... by Dale Kiefer, LE Magazine June 2006 For years, scientists have sought a way to boost one of the body’s most powerful natural antioxidant enzymes: superoxide dismutase (SOD). Present both inside and outside cell membranes, SOD is one of the body’s primary internal anti-oxidant defenses, and plays a critical role in reducing the oxidative stress implicated in atherosclerosis and other life-threatening diseases. Studies have sho ...more...

50. Antiaging skin care by Nicholas Tan ‘Antiaging skin care’ is a very poplar concept in today’s world. Today everyone wants to hide their age using antiaging skin care procedures (and a number of people are successful too). However antiaging skin care is not achieved by any magic potion. ‘Antiaging skin care’ is about discipline. It is about being proactive. Antiaging skin care is retarding the ageing process. Here are a few tips for ...more...

51. New Sources of Hyaluronic Acid by Kristy Annely Recent research into the purification of Hyaluronic acid (HA) from the vitreous humor of fish has shown great promise. This method is highly efficient and easier than derivation from rooster combs and other traditional sources of HA. Specifically, scientists have pinpointed a way to derive highly pure Hyaluronic acid from the vitreous humor of fish. This method has the potential t ...more...

52. Anti-Aging Skin Care Treatment, Products and Tips by Jasdeep Singh Why to let people know your age when you can keep them guessing? But shedding off years from your appreance isnt always a piece of cake. At times, it can present a picture where you are trying a bit too hard which you should avoid. But there are some magic tips which you can always use to hide your age 1) Give special attention to neck while moisturisin ...more...

53. Shilajit is commonly known as the youth of fountain. It is a her... by Dr smith johnson Shilajit General weakness – Shilajit since long has been regarded has a health supplement that had been put under use to revive the lost powers of our body. Shilajit also known as shilajeet is an organo-mineral substance that has a very prehistoric origin. Long ago when our continents were drifting, the present Himalaya were not the mountains but a very fertile area with lots of ...more...

54. Healthy Aging by Senior Fitness.com For many of us, getting older is a constant battle with health, aging, fitness and wrinkles. It can almost seem like you are a captive in a foreign body that cannot possibly be you staring back from the mirror. It is something we all go through, but how well we age depends largely on the choices we made, and the lifestyle we lived, when we were younger. Luckily, for many of us, there are some ...more...

55. Extension of Life by Senior Fitness.com There is no cure for aging. No matter how many promises of miracle potions, lotions and elixirs, there is no cure for aging. Delaying aging as an extension of life is, of course, well within our grasp. However, we have to come to terms with the fact that it takes more than popping a pill for life extension to occur. How we live our lives determines how we age. Youth, like the hear ...more...

56. Managing Your Cholesterol - The Best Way To Prevent Hearth Attac... by Richard Clement Cholesterol is one of the most familiar medical words today. Everyone knows “something” about it , but mostly cholesterol is associated in our mind with something “bad” and “unwanted” that happens to old and overweight people.The facts show that about 20 percent of the U.S. population has high blood cholesterol levels. Actually holesterol is a waxy, fatlike substance (lipid) that your ...more...

57. Yerba Mate: The Powerhouse Nutrient For Healing, Anti-Aging and ... by Carina MacInnes Many think of Yerba Mate as a tea beverage. While the chemical components are quite similar to green tea, it is in fact far more nutritious, because scientific study has shown it to contain nearly all of the necessary life-sustaining vitamins, minerals and nutrients. It has been found to be loaded with an even richer and more potent array of antioxidants than green tea. Yerba ...more...

58. Natural Anti Aging and Bodybuilding Supplements by Fabiola Groshan Experiencing the signs of aging can be rather painful. Some people take the aging process as a normal course of events, whereas others are firmly convinced that they will be forever young. Still, at a certain point in everyone’s life, the aging signs become more and more visible, and we are not talking just about what can be seen at the surface. Skin is said to be a reliable indicator of a person’ ...more...

59. ADULT STEM CELLS: Are these Master Cells the Elixir of Youth? by Paula Rothstein At approximately the age of 40 the body starts to break down at a more rapid rate. Recovery from injury takes longer, cholesterol levels start to rise, as does the blood pressure, hair begins to grey and fine lines set in. Your cancer risk increases as well. If you are not leading a preemptive style approach to maintaining optimal health, you begin to collect health conditions. One o ...more...

60. Sun Damage: A Major Cause Of Wrinkling And Premature Aging by Valerie Goettsch Most of us love the warmth of the sun, but over exposure can cause significant damage to our skin. The sun's ultraviolet rays (UV) can cause our skin to dry out and lose essential oils and decades of tanning, burning and over exposure to the sun may cause changes in our skin's structure. Unprotected skin exposed to the sun can gradually lose essential oi ...more...

61. How Carnosine Protects Against Age-Related Disease by Edward R. Rosick, DO, MPH, MS LE Magazine January 2006 How Carnosine Protects Against Age-Related Disease By Edward R. Rosick, DO, MPH, MS Proteins are the building blocks of life. Comprising amino acid chains, proteins serve both structural and functional roles within the human body. Structural proteins such as collagen give support to bones, tendons, and skin, while functional proteins known as e ...more...

62. Antioxidants, Mitochondrial Damage, and Human Aging by Edward R. Rosick, DO, MPH, MS LE Magazine February 2006 Antioxidants, Mitochondrial Damage, and Human Aging By Edward R. Rosick, DO, MPH, MS Throughout history, scientists have sought strategies for warding off the seemingly inevitable processes of aging and death. In recent decades, the free radical theory of aging has shed light on the degenerative changes that occur as people grow older. ...more...

63. What do you need to know about senior's health by Mansi Gupta As one progresses in age, he retreats in health or fitness. Though senior citizens are counseled to stay fit, it is barely the case like. Numerous natural transformations occur in the body as it moves towards fragility. For instance, the bones and muscles lose their potential reducing the stamina of the body, the kidneys and other internal organs start malfunctioning and the vigor of the skin ...more...

64. The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferatio... by The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells Natalia Martinez1 , Bettina Drescher2 , Heidemarie Riehle1 , Claire Cullmann1 , Hans-Peter Vornlocher3 , Arnold Ganser2 , Gerhard Heil2 , Alfred Nordheim1 , Jürgen Kraut ...more...

65. Longevity - Can Fat Cells Dictate How Long a Human Survives? by C. Bailey-Lloyd/LadyCamelot According to the September Issue of Popular Mechanics, a report written by Jim Wilson explains how human beings may some day have the capability to survive to be 180 (one hundred eighty) years old! According to the September Issue of more...

66. Anti Aging Therapy by Senior Fitness.com Have you been looking for a great anti aging therapy, suitable for over 50’s? At Senior Fitness we are dedicated to vitality, energy and life-long health. There are many ways that you can combat the effects of aging on your body that are both healthy and lasting. Come visit our site and see which anti aging therapy we have that will suit your personal needs. There are a wide range of op ...more...

67. Alcohol and Muscles by Sandra Prior Bodybuilders who like to drink should consider the effects of alcohol on both muscles and hormones. A 1989 study of alcohol found that heavy alcohol consumption damages the heart muscle in one third of the subjects, and skeletal muscles in half of them. It’s very clear that alcohol’s toxic effects on muscles are significant and far more widespread than anyone thought. The study also found ...more...

68. Non-enzymatic glycosylation of a type I collagen matrix: effects... by Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress Antonio D McCarthy , Susana B Etcheverry , Liliana Bruzzone , Gabriela Lettieri , Daniel A Barrio and Ana M Cortizo Cátedra de Bioquímica Patológica and Division Química Analítica, Facultad de Ciencias Exactas, Universidad Nacional de La ...more...

69. Are you chronically dehydrated? by Matt Canham For many of us, when we hear the term dehydration, we immediately think of a man staggering in the desert, or an athlete having just finished a gruelling event. We are correct in a sense, however these are both examples of acute dehydration. You may be surprised to learn there is a far more widespread form — chronic dehydration — that we should all be concerned with. So how ...more...

70. How are Collagen Tablets Used by Anne Harvester You may be familiar with collagen products and probably heard of collagen tablets, but may not necessarily know what they are. You may also be aware of injections that some women take in order to make their lips fuller. This is only one use of a remarkable substance that is necessary for all animal life. What is more...

71. What Is Nuclear Factor-Kappa Beta? by Julius G. Goepp, MD What Is Nuclear Factor-Kappa Beta? By Julius G. Goepp, MD For the past seven years, Life Extension has published extensive articles about chronic inflammation and the numerous diseases it causes, such as cancer, athero-sclerosis, arthritis, dementia, and more. In these articles, we showed how aging people over-express a molecule called nuclear factor-kappa beta, which then ...more...

72. Green Tea For Weight Loss, Anti Aging and Health by Jennifer Kays sappa@anvilcom.com. Best regards Jennifer Kays http://www.sweetmeidicineessentials.com Green Tea For Weight Loss, Anti Aging and Health We have all heard others talking about the great health benefits of green tea. Few of us, until recently, have known that green tea has been used as a medicine in China for at lest 4,000 years to treat everything from pain to depress ...more...

73. Biochemical Clues To Long Lifespan Revealed: Findings Extend Lon... by Children's Hospital, Boston BOSTON -- Researchers at Children's Hospital Boston have discovered how two key cellular influences on lifespan work together, providing insights that may help reveal aging mechanisms in humans. The findings extend longevity research from yeast and worms into mammals, and suggest that longer life results, at least in part, from biochemical interactions that boost cells' ability to resist ...more...

74. Inflammation and Killer Diseases by James Kronefield For many years, medical researchers have thought there may be a common thread that is present in, and maybe the cause of, all disease. There are more and more researchers coming to the conclusion that chronic inflammation plays a role in almost all the major diseases known to man. The logical conclusion, if that's true, is if you can eliminate or control chronic inflammation from t ...more...

75. Antioxidants: Combating Aging and Disease by Sylvia Riley Copyright 2006 Sylvia Riley Wouldn?t we all like to age gracefully (if at all for that matter!) and ward off the wrinkly signs and ill symptoms for as long as possible. Keys to longevity may be more accessible than we think, and it appears our diets play a critical role. Antioxidants are the knights in shining armor that subjugate the attack of free radicals in the body, the hazardous molecu ...more...

76. Anti-Aging by andrew philip If you got the opportunity to read an ancient Ayurvedic texts you would come across a magical herbal supplement known as Shilajit. Shilajit is classified under both rasayana (health rejuvenator) and Vaajikarna (sex tonic). Hence Shilajit is an herbal supplement that has been used as a rasayana since ages. It is extremely beneficial in targeting the free radicals that gets generated with the ...more...

77. Calorie Restriction - An Anti-Aging Diet by GiGi Konwin There was an article printed recently in a special diet and health issue of Scientific American that covered the subject of calorie restriction and its effects on aging. It was significant to note that this article was originally done 10 years ago, yet the subject still remains new today. Chances are, you may not have heard of the calorie restriction concept. It is based on research done ...more...

78. Lifetime Fitness: On Your Way to a Healthier You by Paul C Lifetime Fitness: On Your Way to a Healthier You Many people end up abandoning perfectly good fitness programs and weight-loss regimens before they even lace up their sneakers. Why? Because in a world filled with fast food, instant messaging, and a five-second disease-tracking device, anything without a quick payoff goes against the grain of the typical American instant gratificati ...more...

79. Super Foods Are They The Answer To Diet And Aging by Ian Read Super Foods Are They The Answer To Diet And Aging Studies have unveiled just how enormous the impact of your diet is. Eating the right foods is not just about fewer pounds and greater energy, but can significantly extend the length of your life. 95 per cent of all people die from heart disease, cancer or diabetes - these top three killers all being diet-related. In ...more...

80. Cellular Immortality by Dr. Gregory M. Fahy Cellular Immortality An Exclusive Interview with Stem Cell Pioneer Michael D. West, Ph.D. Dr. Gregory M. Fahy LE: Let’s consider the merits of telomerase therapy vs. stem cell therapy. After capturing telomerase technology for Geron, you left Geron and went full tilt into stem cell research. Explain why. MW: If we age because our cells have a built-in clock that control ...more...

81. How to keep yourself Young and Healthy by Knut Holt The aging process is for the greater part no mystery anymore. It consists for a great part of daily damages done on the macroscopic, tissue, cellular and genetic levels. These add up as the years are passing. These damages have specific causes like oxidating agents, sun beams, mechanical wear and tear, psychological stress, lack of some nutritional components and too much of others, like ...more...

82. Promoting Mitochondrial Health - Nutrients That Optimize Cellula... by Dale Kiefer LE Magazine February 2005 Promoting Mitochondrial Health - Nutrients That Optimize Cellular Energy By Dale Kiefer Mitochondria, the powerhouses in each human cell, have the crucial job of generating energy for use throughout the body. With advancing age and cumulative free radical attack, however, mitochondria can become less efficient, leading to degenerative changes ass ...more...

83. Pomegranate by Sylvia Riley Affectionately known as the ‘jewel of winter’, the pomegranate is receiving growing acclamation for its disease-fighting abilities, largely due to its staggering antioxidant potency. Traditional medicines of the Middle East and India have used the pomegranate for centuries - leaves, skin and rind included - to cure everything from conjunctivitis and sore throats to baldness and hemorrhoids. ...more...

84. Free Radicals: Destructive Scavengers and the Vital Role Antioxi... by Carina MacInnes Several years ago, it was all over the news. Free radicals were damaging - we all had them, and antioxidants were the solution. But what role really do free radicals play in damaging the body, and how are we supposed to best get rid of them? How do antioxidants work and what is the best way of adding them to our diet? 24 hours a day, while the body is constantly working, cells are met ...more...

85. Cinnamon Spice and Everything Nice by Darlene Siddons This tasty spice is a miracle in health benefits, and with our holiday cooking it is used in many bake goods and dishes, so now that we have the cinnamon down off the shelf, lets continue to use it all year round. After you read this article you may even head to the health food store and by the supplement so you get an even more powerful boost. If you are diabetic and/or borderline diabet ...more...

86. Can Scientists Stop the Aging Process? by Royane Real Most of us want to live a long time, but few of us look forward to being really old. Now many of us wonder: why do we have to age? Is aging inevitable? And what can scientists do to slow down the aging process, or stop aging altogether? If you’re still alive, you’re growing older every day. You may not notice it, but you are. When we make that great shif ...more...

87. Andropause and Hair Loss by Cathy Taylor Andropause and hair loss often go hand in hand. Imagine clumps of hair falling off your head, or observing strands of once healthy hair collecting in the shower drain. Maybe you run your hand through your hair and feel it thinning. It can feel daunting and quite scary. Typically, hair loss is a result of an imbalance of male testosterone hormone in the body. Instead of infusing the ...more...

88. Protecting against the lethal effects of chronic inflammation by Life Extension Foundation Protecting against the lethal effects of chronic inflammation People suffering from chronic disease often have elevated levels of C- reactive protein in their blood. C-reactive protein indicates an inflammatory process is going on in the body, but does not identify the specific pro-inflammatory cytokine that may be the underlying cause. Testing for pro-inflammato ...more...

89. Herbal and Home Remedies That Prevent Memory Loss by Susun Weed Even a single family member who is senile or afflicted with Alzheimer's is enough to make anyone dread the possibility. Since women have always lived longer than men, the Ancient Grandmothers have a thing or two to tell us about how to keep our memory sharp until the day we die (at 100+). These remedies are taken from my book New Menopausal Years the Wise Woman Way. They are arranged in order ...more...

90. Four Main Factors Causing High Cholesterol by james ellison Besides diet, other causes of high cholesterol are lifestyle, gender and the heritage of the individual. For some, even maintaining cholesterol at the right levels and being fit and thin will still not prevent the development of high levels of bad cholesterol. Due to heart risk factors besides diet, some people require a very aggressive approach which includes cholesterol lowing medicat ...more...

91. Nine Steps To Stay Younger and Healthier! by Neelima Reddy Even though you have a great health right now, proper steps are essential to maintain the same thing throughout your life. There is no need to take most typical diet and exercise to maintain good health forever. Simple steps which make simple changes in your daily routine are most helpful for you to stay healthy right now and throughout the coming years. The nine steps which ar ...more...

92. The REAL Effects of Alcohol On Your Body - Part 2 of 2 by Marc David marc_david@hotmail.com. Best regards Marc David http://www.justaskmarc.com The REAL Effects of Alcohol On Your Body - Part 2 of 2 This is Part 2 of the continuation of the effects of excessive alcohol on your bodybuilding workouts. 4- Decrease in vitamin and mineral absorption When you consume large quantities of alcohol, your liver is busy converting the alcohol to ac ...more...

93. Natural Anti-Aging Formula Against Bacteria And Viruses? by Farrell Seah Normal aging is accompanied by several physical changes in the body, including decreased muscle mass, increased fat mass, and a decrease in bone density. While the physiological processes behind these changes are very complex and not completely understood, it is now known with absolute certainty that they are governed, at least in part, by the presence of growth hormone (GH) in the body. < ...more...

94. Do You Know Your Antioxidant Score? by Carmen Allard Imagine this…we have the ONLY health assessment device in the world that can measure your health! It can measure one of your most important bio-markers and show you the strength of your immune system. It’s painless, non-invasive and takes only three minutes. The Scanner - Developed at the University of Utah, the Antioxidant Scanner non-invasively scans the palm of a person’s hand ...more...

95. Your Plan for Staying Young by Mitamins Team Preventing aging and growing older with confidence and strength are totally two different things. There is no "cure" for aging, but one can age with care. So if you see advertisements that claim to cure aging, stay away- this is complete nonsense. However much you desire to turn back the clock, a "cure" for aging is nothing more than a magic powder. However, it is well known that meth ...more...

96. "Skin Beauty... Do Antiaging Creams Really Turn Back the Clo... by Warren Matthews If you believe the television advertisements for skin care products, then, your answer would be a definite yes. These TV commercials suggest that if you use this or that product that you too can have a flawless and beautiful complexion and, by subtle inference be happy. But, is this reality or an illusion? It's a combination of both a partial reality and illus ...more...

97. Benefits of Vitamin C by vincent platania Vitamin C is a necessary part of the human diet. Our bodies cannot make Vitamin C, nor to they store vitamin C and so it's essential that you get some vitamin C every day. Interestingly our inability to create Vitamin C is a genetic defect that developed sometime in the past and spread through the human population. It's important for its role in the production of collagen in the body. ...more...

98. Senior Health Fitness by Senior Fitness.com ‘You are only as old as you think you are,’ is something told to many people old and young, but time does not stand still. Before we know it we enter the golden years with grandchildren bouncing on our (hopefully not too stiff) knees and (hopefully) a strong enough back to be able to pick up and hug them and spend quality time doing as much as we possible can. There is also the old ad ...more...

99. Tips for Healthy Skin Year-Round by R.L. Fielding Taking care of your skin is essential all year ‘round. Humidity, harsh weather conditions, and sun exposure are just a few of the elements that affect your skin as the seasons change. Follow these skin care tips from dermatologist Dr. Linda Franks, and you’ll help ensure that you’re promoting healthy skin the whole year through. Winter The winter months can really take a t ...more...

100. 3 Different Types of Diabetes by Donald Mckenzie JR Diabetes is caused by a disruption in insulin production in the body. Insulin is a hormone produced by your pancreas when the level of blood sugar increases. Mainly this happens after a full meal. With the help of insulin, glucose moves from the blood into the cells. The cellular components turn the glucose into energy. When glucose does not enter cells, it stays in the blood and is filtered by th ...more...